Lyre's in St. Louis, MO

Pop's Blue Moon calls itself "A Mindful Bar," and it has receipts: this century-old tavern on The Hill — built with lumber salvaged from the 1904 World's Fair — pours one of St. Louis' deepest non-alcoholic lineups alongside its regular bar. Owner Joshua Grigaitis launched booze-free New Moon N/A Saturdays back in November 2018, and by 2022 Feast Magazine reported that non-alcoholic options accounted for about 30 percent of sales, from Athletic Brewing and WellBeing beers to some ten varieties of Lyre's zero-proof spirits and his own Cheerz NA seltzers. One honest heads-up: alcohol-free here isn't always substance-free — the bar also serves CBD, CBG and delta-8 THC-infused drinks. Live music keeps the tiny room loud most nights.

The Vandy, the Grove cocktail bar from the STL Barkeep team, opened in early 2023 and treats zero-proof drinking as a first-class program. Co-owner and beverage director Patrick Gioia maintains a dedicated Zero Proof Beverages menu: four $10 NA cocktails — Crimson Gimlet, Pack Mule In Recovery, Nojito and Alternative Expression — built on BARE Zero Proof, Lyre's and Ritual alternatives, plus Leitz dealcoholized Pinot Noir and Blanc de Blanc and Gruvi NA beers. Feast Magazine observed the menu 'has just as many NA drinks as it does tequila-based cocktails,' and Gioia's staff even teaches classes on making NA and low-proof cocktails.

Tucked into the lower level of Noto in St. Peters, Bormio channels the Alpine crest — Northern Italy, Switzerland, Austria and beyond — into hearty mountain cooking and one of the St. Louis metro's most serious zero-proof programs. The bar prints a dedicated non-alcoholic menu headlined 'Clear views.': five $13 signature mocktails built on craft NA spirits, from the Ash & Fig (Cut Above zero-proof mezcal, caramelized fig, lime) to a pine-laced Mountain Forager and an NA Espressotini made with Lyre's Amaretti. Best Day Brewing's hazy IPA, Weihenstephaner's NA weissbier and alcohol-removed Mionetto prosecco round out the list. Feast Magazine named the concept — then called Bacaro — its Best New Restaurant of 2024.

The Passport began as Pour Decisions STL, a mobile bar launched in 2020 by married duo Javia Gilliam-Sanford, a certified sommelier, and mixologist Kaje Sanford. After a hit two-year run downtown, the pair relaunched their travel-themed cocktail and wine bar in a two-story Delmar Loop space in November 2025. The globetrotting menu carries a dedicated Spirit Free section — ten alcohol-free cocktails built on Lyre's non-alcoholic spirits, from the yuzu-spiked Japanese Water to a zero-proof Zombie, Mai Tai, and Sicilian Margarita. With vintage mid-century furniture, an upstairs Equinox Lounge, and a sommelier-run wine club, it's one of St. Louis's most polished settings for a spirit-free night out.